Atypical Manifestations of Dengue Fever: A Narrative Review

Shaila Rahman, Amit wazib, Tamanna Bahar


Dengue fever (DF) is an arboviral infection caused by one of four serotypes of the dengue virus. The worldwide burden of DF is high with a low fatality rate. It is endemic in tropical and sub-tropical regions. It is transmitted by mosquito bites. After a certain incubation period, it produces typical symptoms of fever, body ache, and headache with low blood pressure and thrombocytopenia. However, there are several atypical manifestations of DF such as acalculous cholecystitis, hepatitis, fulminant hepatic failure, acute pancreatitis, febrile diarrhea, encephalopathy, seizure, meningitis, encephalitis, acute motor weakness, myocarditis, acute respiratory distress syndrome (ARDS), acute kidney injury (AKI) and myositis, which are often overlooked leading to delayed diagnosis and high morbidity and mortality. This narrative review has compiled different atypical manifestations of DF. This article would be beneficial for clinicians to diagnose DF with atypical presentations early and save many lives by timely interventions.


AKI, ARDS, atypical manifestations, Dengue fever, Myocarditis

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