A Rare Case of Castleman Disease of the Neck: Unicentric Type with Plasma Variant

Harridas Manickam, Suhaimi Yusuf, Ahlam Naila Kori, Azlina Abd Rahman, Norhidayah Jalani, Irfan Mohamad

Abstract


Castleman disease (giant or angio follicular lymph node hyperplasia) is an uncommon lymphoproliferative disorder which is localised to single lymph node (unicentric) or multiple lymph node level systemically (multicentric). It is a very rare disorder characterised by non-cancerous growths. The most common sites of this are mainly thorax (mediastinum or lung hilum) and abdomen. It rarely occurs in the head and neck area. We report a 17-year-old girl who had left neck swelling for 5 years. The excised mass was histopathologically confirmed as Castleman of a rare plasma cell variant, treated with adjuvant radiotherapy. Follow-up after one year showed no recurrence.


Keywords


Castleman disease; lympho proliferative disorder; non-cancerous; plasma cell

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References


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