Aggressive Posterior ROP: Unmonitored Oxygen Therapy Contributed to Blindness in Preterm Infant – A Case Report

Zayani Zohari, Li Yen Chan, Jamalia Rahmat, Zunaina Embong

Abstract


A subtype of retinopathy of prematurity (ROP) with aggressive behaviour is called aggressive posterior retinopathy of prematurity (APROP), which occurs in very preterm infants. We report a case of APROP in a borderline moderate preterm baby who was resuscitated with supplemental unblended oxygen. A premature baby boy was born at 31 weeks gestational age (GA) with a birth weight of 1500 grams in a rural hospital. He was intubated at birth due to respiratory distress syndrome and received unmonitored supplemental oxygen for 5 days. ROP screening at 36 weeks GA showed features of stage 4a ROP in bilateral eyes, which progressed to stage 5 ROP at 43 weeks GA. He was diagnosed to have APROP in both eyes and was treated surgically. APROP is a rapidly progressive severe form of ROP. Our report showed that a high flow of unmonitored oxygen supply could lead to severe ROP. Thus, an earlier ROP screening may be of value in this group of infants.

Keywords


Aggressive posterior retinopathy of prematurity, premature infant, supplemental oxygen

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References


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