Revascularization medicaments of the traumatized immature permanent incisor- A case report

Norsamsu Arni Samsudin, Chitra Devi Sathy Velloo, Nurulaqmar Iwani Samsudin, Nik Rozainah Nik Abdul Ghani

Abstract


Dental trauma to teeth in children often causes apical periodontitis and pulp necrosis in immature permanent teeth. Subsequently, it may lead to cessation of dentinal wall thickening and complete root development. This case report presents a revascularization therapy of the traumatized permanent upper left central incisor tooth in an 8-year-old boy. The tooth had suffered the traumatic injury about two months prior the first consultation that cause pulp necrosis and impede root development. Revascularization therapy was done onto his traumatized tooth. A sterile sodium chloride or normal saline was used solely as a canal disinfectant material and double antibiotic paste (DAP) as an intracanal medicament. Good radiographic and clinical outcomes were observed during the 12 months review since the beginning of the revascularization therapy. Considering the continuous root development and apical closed, it can be concluded that the sterile normal saline disinfectant and DAP as intracanal medicament serves a promising good outcome in an asymptomatic and immature necrotic permanent tooth.


Keywords


health sciences

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References


Ahmed Kamel Abd El Nasser1 * NMAK and ESAE. Evaluation of the Success Rate of Revascularization Technique Using Leukocyte-Platelet-Rich Fibrin (L-PRF) Concentrate Compared to Blood Clot as a Scaffold. EC Dental Science 2019;4:623–30.

Arango-Gómez E, Nino-Barrera JL, Nino G, Jordan F, Sossa-Rojas H. Pulp revascularization with and without platelet-rich plasma in two anterior teeth with horizontal radicular fractures: a case report. Restor Dent Endod. 2019;44(4):1–10.

Ayoub S, Cheayto A, Bassam S, Najar M, Berbéri A, Fayyad-Kazan M. The Effects of Intracanal Irrigants and Medicaments on Dental-Derived Stem Cells Fate in Regenerative Endodontics: An update. Stem Cell Reviews and Reports. 2020; 16: 650–660.

Azami AS, Ebadifard AF, Pournaghi AF, Rezapour A, Moradi JM, Moosavi A, et al. Prevalence,etiology and types of dental trauma in children and adolescent:systematic review and meta-analysis. Med J Islam Repub Iran. 2015;29(234):591–6.

Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis:new treatment protocol? J Endod. 2004;30(4):196–200.

Becerra P, Ricucci D, Loghin S, Gibbs JL, Lin LM. Histologic study of a human immature permanent premolar with chronic apical abscess after revascularization/revitalization. J Endod. 2014;40(1):133–9.

Borin-Moura L, Azambuja-Carvalho P, Daer-de-Faria G, Barros-Gonçalves L, Kirst-Post L, Braga-Xavier C. A 10-year retrospective study of dental trauma in permanent dentition. Rev Esp Cir Oral Maxilofac. 2018;40(2):65–70.

Bourguignon C, Cohenca N, Lauridsen E, Flores MT, O’Connell AC, Day PF, et al. International Association of Dental Traumatology guidelines for the management of traumatic dental injuries: 1. Fractures and luxations. Dent Traumatol. 2020;36(4):314–30.

Burkhardt MA, Gerber I, Moshfegh C, Lucas MS, Waser J, Emmert MY, et al. Clot-entrapped blood cells in synergy with human mesenchymal stem cells create a pro-angiogenic healing response. Biomater Sci. 2017;5(10):2009–23.

Chan EKM, Desmeules M, Cielecki M, Dabbagh B, Ferraz dos Santos B. Longitudinal Cohort Study of Regenerative Endodontic Treatment for Immature Necrotic Permanent Teeth. J Endod. 2017;43(3):395–400.

Cymerman JJ, Nosrat A. Regenerative Endodontic Treatment as a Biologically Based Approach for Non-Surgical Retreatment of Immature Teeth. J Endod [Internet]. 2020 Jan;46(1):44–50. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0099239919307496

de-Jesus-Soares A, Prado MC, Nardello LCL, Pereira AC, Cerqueira-Neto ACCL, Nagata JY, et al. Clinical and Molecular Microbiological Evaluation of Regenerative Endodontic Procedures in Immature Permanent Teeth. J Endod [Internet]. 2020 Oct;46(10):1448–54. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0099239920304921

Flake NM, Gibbs JL, Diogenes A, Hargreaves KM, Khan AA. A standardized novel method to measure radiographic root changes after endodontic therapy in immature teeth. J Endod. 2014;40(1):46–50.

Hameed M, Gul M, Ghafoor R, Badar S. Management of Immature Necrotic Permanent Teeth with Regenerative Endodontic Procedures - A Review of Literature. J Pak Med Assoc [Internet]. 2019;69(10):1. Available from: https://www.ejmanager.com/fulltextpdf.php?mno=294366

Jiang X, Liu H, Peng C. Clinical and Radiographic Assessment of the Efficacy of a Collagen Membrane in Regenerative Endodontics: A Randomized, Controlled Clinical Trial. J Endod [Internet]. 2017 Sep;43(9):1465–71. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0099239917304831

John A, Hegde AM, Shetty P, Shetty S. Revascularization of an Immature Permanent Central Incisor with Complicated Crown Root Fracture: A Case Report. Int J Clin Pediatr Dent. 2019;12(1):59–63.

Khoshkhounejad M, Shokouhinejad N, Pirmoazen S. Regenerative Endodontic Treatment: Report of Two Cases with Different Clinical Management and Outcomes. J Dent (Tehran) [Internet]. 2015;12(6):460–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26884781%0Ahttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC4754573

Lee LW, Hsiao SH, Lin YH, Chen PY, Lee YL, Hung WC. Outcomes of necrotic immature open-apex central incisors treated by MTA apexification using poly(ε-caprolactone) fiber mesh as an apical barrier. J Formos Med Assoc. 2019;118(1P2):362–70.

Leite MCF, Fereira CM, De Almeida Gomes F, Pappen FG, Tedesco TK, Calvo AFB, et al. Regenerative endodontic treatment options for immature permanent teeth: A case report with 21-month follow-up. G Ital Endod. 2020;34(1):35–40.

Mente J, Hage N, Pfefferle T, Koch MJ, Dreyhaupt J, Staehle HJ, et al. Mineral Trioxide Aggregate Apical Plugs in Teeth with Open Apical Foramina: A Retrospective Analysis of Treatment Outcome. J Endod [Internet]. 2009 Oct;35(10):1354–8. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0099239909005020

Miltiadous MEA, Floratos SG. Regenerative endodontic treatment as a retreatment option for a tooth with open apex - A case report. Braz Dent J. 2015;26(5):552–6.

Mittmann CW, Kostka E, Ballout H, Preus M, Preissner R, Karaman M, et al. Outcome of revascularization therapy in traumatized immature incisors. BMC Oral Health. 2020;20(1):207.

Mohammadi Z, Dummer PMH. Properties and applications of calcium hydroxide in endodontics and dental traumatology. Int Endod J. 2011;44(8):697–730.

Nagarajappa R, Ramesh G, Uthappa R, Kannan SPK, Shaikh S. Risk factors and patterns of traumatic dental injuries among Indian adolescents. J Dent Sci. 2020;15(1):96–103.

Nagata JY, Figueiredo De Almeida Gomes BP, Rocha Lima TF, Murakami LS, De Faria DE, Campos GR, et al. Traumatized immature teeth treated with 2 protocols of pulp revascularization. J Endod. 2014;40(5):606–12.

Nagata JY, Rocha-Lima TF, Gomes BP, Ferraz CC, Zaia AA, Souza-Filho FJ, et al. Pulp revascularization for immature replanted teeth: A case report. Aust Dent J. 2015;60(3):416–20.

Nagaveni N, Poornima P, Khan M. A Comparative Evaluation of Revascularization Done in Traumatized Immature, Necrotic Anterior Teeth with and without Platelet-rich Fibrin:A Case Report. Int J Clin Pediatr Dent. 2020;13(1):98–102.

Nageh M, Ahmed GM, El-Baz AA. Using a modified Revascularization techniique with Platelet-rich Fibrin: A Clinical Study. J Endod. 2018;44(10):1526–33.

Nalawade T, Sogi SP, Bhat K. Bactericidal activity of propylene glycol, glycerine, polyethylene glycol 400, and polyethylene glycol 1000 against selected microorganisms. J Int Soc Prev Community Dent. 2015;5(2):114.

Nosrat A, Seifi A, Asgary S. Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: A review and report of two cases with a new biomaterial. J Endod. 2011;37(4):562–7.

Paudel KR, Jaiswal A, Parajuli U, Bajracharya M. Different pharmacological solutions in intracanal irrigation. Nepal Medical College journal.2011;13: 111-114.

Petridis X, van der Sluis LWM, Dijkstra RJB, Brinker MGL, van der Mei HC, Harmsen MC. Secreted products of oral bacteria and biofilms impede mineralization of apical papilla stem cells in TLR-, species-, and culture-dependent fashion. Sci Rep [Internet]. 2018 Dec 21;8(1):12529. Available from: http://www.nature.com/articles/s41598-018-30658-5

Sabbagh S, Shirazi AS, Torabzadeh H. Double antibiotic paste for management of external inflammatory root resorption. Iran Endod J. 2018;13(4):569–72.

Saoud TMA, Zaazou A, Nabil A, Moussa S, Lin LM, Gibbs JL. Clinical and radiographic outcomes of traumatized immature permanent necrotic teeth after revascularization/revitalization therapy. J Endod. 2014;40(12):1946–52.

Sharma R, Kumar V, Logani A, Chawla A, Sharma S, Koli B. Effect of gravity on periapical extrusion of irrigating solution with different irrigation protocols in immature anterior teeth. Eur Endod J. 2020;5(2):150–4.

Silva MHC, Campos CN, Coelho MS. Revascularization of an Immature Tooth with Apical Periodontitis Using Calcium Hydroxide: A 3 year Follow-up. Open Dent J. 2015;9:482–5.

Ulusoy AT, Turedi I, Muge C, Cehreli ZC. Evaluation of Blood Clot, Platelet-rich Plasma, Platelet-rich Fibrin and Platelet Pellet as Scaffolds in Regenerative Endoodntic Treatment: A Prospective Randomized Trial. J Endod. 2019;45(5):560–6.

Valverde ME, Baca P, Ceballos L, Fuentes MV, Ruiz-Linares M, Ferrer-Luque CM. Antibacterial efficacy of several intracanal medicaments for endodontic therapy. Dent Mater J. 2017;36(3):319–24.

Velmurugan N, Sooriaprakas C, Jain P. Apical Extrusion of Irrigants in Immature Permanent Teeth by Using EndoVac and Needle Irrigation: An In Vitro Study. J Dent (Tehran). 2014;11(4):433–9.

Viduskalne I, Care R. Analysis of the crown fractures and factors affecting pulp survival due to dental trauma. Stomatologija. 2010;12:109–115.

Wigler R, Kaufman AY, Lin S, Steinbock N, Hazan-Molina H, Torneck CD. Revascularization: A treatment for permanent teeth with necrotic pulp and incomplete root development. J Endod. 2013;39(3):319–26.




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